What we do ...
Novoviah works closely with your research and development team anywhere in the world to create a Novoleukin Test System customised to your needs and your antigens.
Our Platform
We make monitoring for antigen-specific T cells easy and sensitive for a clinical trial, by leveraging exceptional quality whole blood incubation with antigen at the trial site with standardised high-performance immunoassay at the central lab.
Novoleukin Test
The key, proprietary intellectual property is the Novoleukin test system, a “whole blood antigen-stimulated cytokine release assay” which is substantially more sensitive than conventional fresh PBMC-based ELISpot assay (e.g. for detection of gluten-reactive CD4+ T cells in celiac disease).
Celiac Disease
Novoviah has extensive experience of the Novoleukin Test System in Celiac Disease. The Novoleukin-C test for gluten-specific T cells associated with celiac disease is reliable even in patients who have not completed a gluten food challenge. This is a landmark achievement in the field.
Other Applications
Novoviah’s aspiration is to have a Novoleukin Test System available for a wide range of antigens relevant to immune disease, therapies and vaccines, and to explore their clinical utility as diagnostics or monitoring tools.
Why choose the Novoleukin test system?
Precision
A “whole blood antigen-stimulated cytokine release assay” which is substantially more sensitive.
Simplicity
The protocol for blood collection and processing is simple and reproducible, to enable easy rollout across multiple sites.
CUSTOMISED
The Novoleukin Test System comprises three key elements: test kit and protocol, specific stimulation of cytokine release and central Lab Performing ultrasensitive cytokine assay.
Our Novoleukin T-cell testing system detects T cells when others don’t. Contact us today or click the button below to learn more and how our system may fit your appliation.
NovoGluten for convenient, consistent and credible in gluten challenges throughout your program.
Standardized gluten powder for gluten challenges.
Building and understanding of dose response.
Same batch for your entire program from concept to approval.
75-80% pure gluten protein, low FODMAPs and pathogen free.
Prepackaged servings to be mixed with liquid in a NovoGluten shaker.
Extensive
charcterization.
Gluten food challenges must be tolerable and potent to inform clinical care and facilitate study endpoints.
NovoFind T-cell Epitome Mappping Platform
Revolutionary drug discovery platform for T cell mediated autoimmune diseases, infections, cancers and vaccine developments.
Development and design of an epitome mapping clinical trial.
Full CRO clinical trial services as required.
Leverage Novoviah's expertise in epitome mapping and clinical trials.
Customise your Novoleukin test.
Contact us today or click the button below to learn more and how our system may fit your appliation.
Our Executive Team & Founders
"Novoviah’s Founders are passionate about simple high performance T cell testing as diagnostic and monitoring tools accelerating pharmaceutical development, providing a new class of diagnostics, and allowing personalised treatment.
Novoviah’s Novoleukin Test System has widespread application measuring rare antigen-specific T cells in autoimmunity, infectious diseases, cancer, vaccine and immunotherapy development, or as a powerful new clinical research tool.
Novoviah has been built on our Founders’ over 20 years’ experience in discovery and commercialization of diagnostics and therapeutics for celiac disease and other immune diseases. Our Founders aim to bring simplicity and highest quality outcomes to support pharmas and biotech in preclinical and early clinical development of immunotherapy."